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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Translational Pancreatic Cancer Research - From Understanding of Mechanisms to Novel Clinical Trials (Paperback, 1st ed. 2020)
Loot Price: R2,751
Discovery Miles 27 510
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Translational Pancreatic Cancer Research - From Understanding of Mechanisms to Novel Clinical Trials (Paperback, 1st ed. 2020)
Series: Molecular and Translational Medicine
Expected to ship within 10 - 15 working days
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This book incorporates a multi-disciplinary approach to present how
research results can be translated into clinical trials. The first
part begins with a chapter on variants of pancreatic cancer,
precursor lesions and groups of people at risk to developing the
disease. There is a particular focus on intraductal papillary
mucinous neoplasia as a large-scale clinical challenge in
pancreatology. The next two parts focus on diagnosis, biomarkers
and stratification that emphasize how various approaches to
biomarker development are important as both prognostic and
predictive tools. The final part consists of personalized treatment
approaches that include preclinical models of pancreatic cancer and
stromal, epigenetic and metabolism targeting as promising
approaches to be translated into early phase clinical trials.
Chapters within this part also deal with approaches that are close
to being implemented in clinical practice or are already being
tested in (early) clinical trials, such as those that targeting the
immune systems and strategies to overcome immunotherapy resistance;
phase 1 clinical trials and translational approaches in surgical
treatment. Written by experts in their fields, Translational
Pancreatic Cancer Research provides an outlook towards future
directions by integrating information both from basic and clinical
research and though demonstrating pathways to better understanding
pancreatic cancer and current approaches to translating these into
clinical practice.
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