Overview of Genetic Factors & Environmental Triggers in the Pathogenesis of Tourette's Syndrome (Paperback)

Tourette's syndrome (TS) is an inheritable, childhood-onset neuropsychiatric disorder characterised by the presence of motor and phonic tics. Despite decades of extensive studies, the exact disease aetiology remains poorly understood. It is believed that susceptibility to TS is determined by the interactions of multiple genetic loci with unknown environmental factors. As a result, a great deal of research has been focused on identifying TS susceptibility genes. Thus far, at least 12 susceptibility loci have been suggested by genome-wide screenings, but none of them has been replicated probably due to genetic heterogeneity. Candidate gene approach has also suggested evidence for several genes relevant to neuronal signalling such as dopamine receptor and serotonin receptor. This book discusses the current state of genetic studies in TS susceptibility.

General

Imprint:	nova science publishers
Country of origin:	United States
Release date:	October 2010
First published:	September 2010
Authors:	Cong-Yi Wang • Shi-Guo Liu • Ping Yang • Zhimin Miao • Qian Dong • Changgui Li • Wei Wang
Dimensions:	140 x 215 x 7mm (L x W x T)
Format:	Paperback
Pages:	59
ISBN-13:	978-1-61668-748-9
Categories:	Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
LSN:	1-61668-748-7
Barcode:	9781616687489

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