Use of Biomarkers in Assessing Health and Environmental Impacts of Chemical Pollutants (Paperback, Softcover reprint of the original 1st ed. 1993)

Biological markers (biomarkers) are useful tools for understanding the nature and extent of human exposure and risk from environmental toxicants. Biomarkers are classified into three basic categories: exposure, effect, or susceptibility. A marker of exposure is the product of the interaction between a target cell or molecule and a foreign substance (NAS, 1989). These markers can be used to determine the biologically effective dose necessary to elicit a particular physiological change in an organism. A marker of effect is a biochemical or physiological change in an organism that can predict the onset of adverse health effects resulting from a given exposure. Lastly, markers of susceptibility act as indicators of an inherent or acquired tendency of an organism to experience an adverse health effect (NAS, 1989). These markers are already used to detect a variety of diseases and show great promise for developing a better understanding of the mechanicisms of disease. Additionally, biomarkers can be used to establish a more rational basis for quantitative risk extrapolation between species, as weIl as to obtain more precise estimates of the time of critical exposure. These markers can also prove helpful in identifying potentially damaging exposures before the onset of adverse health effects. Biomarkers serve as a valuable exposure assessment tool because they take into account exposure from all routes and integrate exposure from all sources. They have the potential to yield better risk estimates than current monitoring and modeling protocols. In lune 1992, Dr. Travis and Dr.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	NATO Science Series A:, 250
Release date:	June 2013
First published:	1993
Editors:	Curtis C. Travis
Dimensions:	235 x 155 x 15mm (L x W x T)
Format:	Paperback
Pages:	286
Edition:	Softcover reprint of the original 1st ed. 1993
ISBN-13:	978-1-4899-2054-6
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Earth & environment > The environment > Management of land & natural resources Books > Professional & Technical > Environmental engineering & technology > General Books > Science & Mathematics > Biology, life sciences > Botany & plant sciences > General Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > General Books > Earth & environment > The environment > Waste management > General
LSN:	1-4899-2054-4
Barcode:	9781489920546

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