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Stereoselective Heterocycle Synthesis via Alkene Difunctionalization - Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation (Paperback, Softcover reprint of the original 1st ed. 2018)
Loot Price: R3,812
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Stereoselective Heterocycle Synthesis via Alkene Difunctionalization - Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation (Paperback, Softcover reprint of the original 1st ed. 2018)
Series: Springer Theses
Expected to ship within 10 - 15 working days
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This book investigates the use of palladium modified by bulky
ligands as catalysts for new chemical transformations that rapidly
assemble several classes of complex heterocyles. It documents the
development of new chemical reactions involving carbon-carbon (C-C)
and carbon-halogen (C-X) bond formation in the context of alkene
difunctionalization and dearomatization reactions. Due to the
ubiquity of heterocycles in bioactive natural products and
life-improving pharmaceutical treatments, a long-term goal for
synthetic organic chemists has been to develop novel and creative
heterocycle syntheses that illicit a high degree of product
diversity and are characterized by mild reaction conditions and
limited waste production. A considerable fraction of leading
pharmaceutical drugs contain at least one heterocycle within their
chemical structure, and their prevalence in these technologies is
strong evidence that the fundamental curiosities of organic
chemistry lead to real-world solutions for the health and wellness
of the global population.
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