The issue of male germ line mutagenesis and the effects on
developmental defects in the next generation has become
increasingly high profile over recent years. Mutations are thought
to be becoming more prevalent as a result of: exposure to chemicals
in the environment, anti cancer regimes that use genotoxic agents
and assisted conception techniques. In addition to the increasing
frequency of mutations in the general population, attention is also
being given to the effects of epigenetic events on future
generations. Male-mediated Developmental Toxicity discusses these
issues comprehensively and includes further analysis on the
fundamental mechanisms of mutations. With both clinical and
experimental sections, written by leading experts in the field,
this book will appeal to both medical practitioners and
researchers.
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