Books > Science & Mathematics > Biology, life sciences > Biochemistry > Enzymology
|
Buy Now
Protein Tyrosine Kinases - From Inhibitors to Useful Drugs (Hardcover, 2006 ed.)
Loot Price: R5,458
Discovery Miles 54 580
|
|
Protein Tyrosine Kinases - From Inhibitors to Useful Drugs (Hardcover, 2006 ed.)
Series: Cancer Drug Discovery and Development
Expected to ship within 10 - 15 working days
|
Leading researchers, from the Novartis group that pioneered
Gleevec/Gliveca"[ and around the world, comprehensively survey the
state of the art in the drug discovery processes (bio- and
chemoinformatics, structural biology, profiling, generation of
resistance, etc.) aimed at generating PTK inhibitors for the
treatment of various diseases, including cancer. Highlights include
a discussion of the rationale and the progress made towards
generating "selective" low molecular-weight kinase inhibitors; an
analysis of the normal function, role in disease, and application
of platelet-derived growth factor antagonists; and a summary of the
factors involved in successful structure-based drug design.
Additional chapters address the advantages and disadvantages of in
vivo preclinical models for testing protein kinase inhibitors with
antitumor activity and the utility of different methods in the drug
discovery and development process for determining "on-target" vs
"off-target" effects of kinase inhibitors.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.