As a result of the Process Analytical Technologies (PAT) initiative
launched by the U.S. Food and Drug Administration (FDA), analytical
development is receiving more attention within the pharmaceutical
industry. Illustrating the importance of analytical methodologies,
Thermal Analysis of Pharmaceuticals presents reliable and versatile
characterization tools for the successful development of
pharmaceutical products. It draws attention to the most widely
applicable methods and demonstrates how to interpret the associated
data.
The book opens with the first three chapters devoted to
differential scanning calorimetry (DSC), the most commonly used
thermal method. These chapters cover the principles, optimal use,
and pharmaceutical applications of the method. Subsequent chapters
explore modulated temperature DSC, thermogravimetric analysis,
thermal microscopy, microcalorimetry, high sensitivity DSC, dynamic
mechanical analysis, and thermally stimulated current, all of which
have attracted great interest within the pharmaceutical field. The
chapters include theoretical background, measurement optimization,
and pharmaceutical applications of each technique.
Exploring important techniques for characterizing the physical
structure and properties of pharmaceutical materials, Thermal
Analysis of Pharmaceuticals achieves an ideal balance in the depth,
relevance, and accessibility of topics presented. The book provides
an excellent overview of this key area in pharmaceutical
development.
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