Oral Exfoliative Cytology is a cost effective and perhaps the best
procedure for the initial evaluation and diagnosis of oral lesions.
It is simple, safe and reliable, especially in population-based
screening programs, where repeated samples might be
required.Liquid-based cytology, since its inception in the 1990s,
has shown significant advantages over conventional exfoliative
cytology. Studies in cervical cytology have shown that the LBC
reduces the problems related to sampling and preparation of better
smears. Blood, inflammation and mucus are reduced and cells are
distributed randomly throughout the slide. The clear background
thus obtained enhances sensitivity and quality. As compared to
conventional smears, the use of liquid-based preparations has shown
to greatly reduce the number of slides that are unsatisfactory, or
satisfactory but limited by specimen artifacts, diminishing the
false negative results.The book highlights the role of liquid based
cytology in oral lesions and its comparison with conventional brush
cytology.
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