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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Experimental Lung Cancer - Carcinogenesis and Bioassays International Symposium Held at the Battelle Seattle Research Center Seattle, WA, USA, June 23-26, 1974 (Paperback, Softcover reprint of the original 1st ed. 1974)
Loot Price: R1,730
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Experimental Lung Cancer - Carcinogenesis and Bioassays International Symposium Held at the Battelle Seattle Research Center Seattle, WA, USA, June 23-26, 1974 (Paperback, Softcover reprint of the original 1st ed. 1974)
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These are the proceedings of the international symposium on
"Experi- mental Respiratory Carcinogenesis and Bioassays", held
from 23 to 26 June 1974 at the Battelle Seattle Research Center,
Seattle, Wash., USA. Human lung cancer is already very common in
industrialized countries, and its incidence is increasing. This
increase involves mainly epi- dermoid and small-cell carcinoma.
Evidence is accumulating that these tumors are associated with such
exogenic factors as automobile exhaust, asbestos, chemicals,
cigarette smoke, and radionuclides. These pro- ceedings are
concerned with finding the most suitable experimental designs for
investigating the genesis of these particular types of tumor, and
with the development of specific bioassays to test sus- pected
carcinogens. Spontaneous epidermoid and small-cell carcinomas are
extremely rare in the respiratory organs of animals, and it has
proved rather diffi- cult until recently to produce them
experimentally. Epidermoid carci- nomas are now readily obtained by
using methods of intratracheal in- stillation of carcinogens with
particulate materials such as that described by SAFFIOTTI and
co-workers, which is the technique most frequently mentioned in
these proceedings. While the experimental production of small-cell
carcinomas has remained difficult, it is described by two authors
in this volume.
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