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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical)
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Modelling in Molecular Biology (Hardcover, 2004 ed.)
Loot Price: R4,537
Discovery Miles 45 370
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Modelling in Molecular Biology (Hardcover, 2004 ed.)
Series: Natural Computing Series
Expected to ship within 12 - 17 working days
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This volume is based on the workshop Modelling in Molecular Biology
that tookplacein2002inSingapore.
Themaingoaloftheworkshopwastopresent models/methods used in solving
some fundamental problems in biosciences. The volume consists of a
selection of papers presented at the workshop as well as of some
other papers that are included so that the presentation of the
theme of the workshop is broader and more balanced. As a matter of
fact we feel that the collection of papers comprising this volume
represents a wide spectrum of quite diverse ideas and trends. The
paper by D. A. Beard et al. explores the common thesis that und-
standingthebehaviouroflargeinteractingsystemsofmanyenzymesandre-
tants underlies the modelling and simulation of whole-cell systems.
Moreover, the models need to represent the basic stoichiometry,
with balanced che- cal reactions and the conservation of mass,
energy and charge. The authors discuss the stoichiometric and then
kinetic details of approaches to modelling and simulation of
biochemical systems. P. R. A. Campos et al. are concerned with
models of evolution and adaptation (which is essential for precise
- derstanding of molecular phylogeny). In particular, their paper
is concerned with the rate of adaptation of asexual organisms(which
is important because it in?uences the speed of the assumed
molecular clock). It is known that for such organisms the rate of
adaptation does not steadily increase with the - creasing rate of
advantageous mutations, and this paper studies the mutual
interference of two advantageous mutants that are each initially
present in only a single organism."
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