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Cellular Effects of Heavy Metals (Paperback, 2011 ed.)
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Cellular Effects of Heavy Metals (Paperback, 2011 ed.)
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The term "heavy metals" is used as a group name of toxic metals and
metalloids (semimetals) causing contaminations and ecotoxicity. In
strict chemical sense the density of heavy metals is higher than 5
g/cm3. From biological point of view as microelements they can be
divided into two major groups. a. For their physiological function
organisms and cells require essential microelements such as iron,
chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The
other group of heavy metals is toxic to the health or environment.
Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni,
Pb, Sn, Tl. The toxicity of heavy metals is well known at
organizational level, while less attention has been paid to their
cellular effects. This book describes the toxicity of heavy metals
on microorganisms, yeast, plant and animal cells. Other chapters of
the book deal with their genotoxic, mutagenic and carcinogenic
effects. The toxicity of several metals touch upon the aspects of
environmental hazard, ecosystems and human health. Among the
cellular responses of heavy metals irregularities in cellular
mechanisms such as gene expression, protein folding, stress
signaling pathways are among the most important ones. The final
chapters deal with biosensors and removal of heavy metals. As
everybody is eating, drinking and exposed to heavy metals on a
daily basis, the spirit of the book will attract a wide audience.
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