From a process that from the days of Vir chow and Rokitansky,
primarily stimulated the relatively narrow interest of
pathologists, amyloidosis has risen full-blown as one of the most
important of disease complexes. Its presence dominat: es the
lesions of Alzheimer's disease, a disease affecting an estimated 2.
5 million people in the U. S. A. and thereby closely rivaling
stroke as the third most common cause of death. If, as it has been
de scribed, Alzheimer's disease is the "Disease of the Century,"
then amy loidosis is the Disease Complex of the Ages. It affects in
one or more of its manifestations every organ of the body, and is
at least as old as the afflicted Egyptian mummies of the pyramids.
With an increasing percentage of older individuals amyloid of the
senior population becomes increasingly more frequent. The subjects
covered in this Symposium range through almost every clinical
medical specialty. From an average of one paper in each of the past
three Symposiums, the explosive interest in cerebral amyloidosis
has led to the presentation of 12 papers on this subject in the
present volume. The genetically predisposed familial amyloidotic
processes, such as the polyneuropathies and familial Mediterranean
fever have also stimulated ex tensive and intriguing investigations
which have revealed the striking effect of a single amino acid
substitution in transforming a normal protein into. a lethal
"amyloidogenic" one."
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Release date: |
October 2011 |
First published: |
1986 |
Editors: |
George G. Glenner
|
Dimensions: |
254 x 178 x 44mm (L x W x T) |
Format: |
Paperback
|
Pages: |
858 |
Edition: |
Softcover reprint of the original 1st ed. 1986 |
ISBN-13: |
978-1-4612-9292-0 |
Categories: |
Books >
Medicine >
Other branches of medicine >
Psychiatry
Promotions
|
LSN: |
1-4612-9292-1 |
Barcode: |
9781461292920 |
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