A successful vaccine for the prevention and/or immunotherapy
against HIV/AIDS is one of the prominent challenges of the 21st
century. To date, all human vaccine trials against this
virus/disease have resulted in failure, or at best have shown very
low efficacy. The scientific community dealing with HIV/AIDS has
unanimously proposed a focus on basic science, with the intention
of identifying correlates of protection that can serve as guides in
developing and evaluating vaccine preparation. However, Nature
seems to have already found several ways of dealing with infections
by HIV and related primate lentiviruses, either by resisting
infection or, once infected, avoiding immune damage and
immunodeficiency.
"Models of Protection Against HIV/SIV" will allow for an
in-depth reflection on the perspectives for vaccine and therapy
research derived from important recent studies. It will be authored
by some of the most well known specialists in the field of HIV
resistance/protection: including F. Barre-Sinoussi (2008 Nobel
Prize for Medicine winner), B. Walker, S. Rowland-Jones, A.
Telenti, M. Lederman and F. Plummer.
This book is structured in a unique way, looking at three models
of resistance/protection separately and then comparing the models
against one another to provide its readership with a detailed
examination of the research that is most predominant in the search
for a vaccine. This structure presents the information in an
easy-to-understand format and gives the book a cross-discipline
appeal -- an important reference for those in the scientific
community, medical care, public health and academia alike.
Providesextensive descriptions and comparisons onthe different
models of protection agains HIV/AIDSComprehensive writing and
illustrationsContributors are among the most eminent specialists in
the field"
General
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