G protein-coupled receptors (GPCRs) constitute the largest
superfamily of cell surface receptors that regulate a variety of
cell functions. Over the past few decades great progress has been
made in defining the roles of intracellular trafficking in
controlling the functionality of the receptors as well as in the
development of various human diseases. This volume of Progress in
Molecular Biology and Translational Science reviews the recent
understanding of GPCR trafficking regulators and molecular
mechanisms.
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