Patients with advanced breast or prostate cancers usually
develop bone metastases. The principal complications resulting from
metastatic bone disease are pain, spinal cord compression,
pathologic fractures and bone marrow suppression. Improving the
management of bone metastases is crucial to quality of life for
patients with breast and prostate cancer.
Advances in understanding of the molecular mechanisms underlying
the pathophysiology of bone metastasis are driving the development
of new therapeutic strategies.
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