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New Concepts in Viral Heart Disease - Virology, Immunology and Clinical Management (Paperback, Softcover reprint of the original 1st ed. 1988)
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New Concepts in Viral Heart Disease - Virology, Immunology and Clinical Management (Paperback, Softcover reprint of the original 1st ed. 1988)
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The recent rapid advances in our knowledge of immunological and
virological mechanisms involved in the pathogenesis of viral heart
disease makes it difficult for everybody working in this field to
keep up with the latest developments. How ever, much of what we
know is still circumstantial and only vaguely substained.
Interdisciplinary understanding and cooperation thus seems
necessary to get a better insight into the mechanisms by which
viruses may initiate immunological organ-specific tissue injury and
disease! This volume evolved out of an international symposium by
the same title held on May 25. -28. , 1988 in Tegernsee, near
Munich, of which a wide spectrum ofim munological, virological,
diagnostical and clinical problems was covered. Both review
articles and new experimental and clinical data are included in
this volume to give the reader an up-to-date information about
current concepts and future aspects. Chapter I serves as an
excellent introduction to the epidemiology and natural history of
dilated cardiomyopathy / viral heart disease. Although a definite
viral etiology in myocarditis and dilated cardiomyopathy is often
difficult to establish, epidemiological and serological data
incriminate a viral etiology underlying many cases of "dilated
cardiomyopathy". Chapters II and III describe the current think ing
on virological and immunological mechanisms involved in the
pathogenesis of viral heart disease. Among others virus topism,
virus persistance, possible mecha nisms and genetic basis of
post-infection autoimmunity, and the virus-interaction with the
immune system are discussed.
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