The processes of tumor metastasis, apoptosis and anti-tumor
immune response are among the most complex yet rapidly advancing
fields in the area of cancer research. This monogaph presents a
comprehensive coverage of the recent advances in the various key
concepts in these fundamental aspects of human cancer. It would be
of particular interest to members of the cancer research community,
especially those who are actively involved in the study of basic
and translational aspects of human cancer. Specifically, this
volume includes authentic subject reviews by leading experts on the
following aspects:
- Control of tumor cell motility
- Role of tumor-cell adhesion and migration in organ-selective
metastasis-formation
- Tumor heterogeneity in relation to invasion and metastasis and
its clinical implications
- Tumor angiogenesis, angioprevention, anti-angiogenic therapies
and response
- Role of apoptosis in the development, progression and therapy
of cancer
- Role of macrophages in tumor development and metastasis
- Pathways of macrophage-mediated tumor progression
- Abnormal variation of immune response against cancer
- Immunological aspects of Marek s disease virus (MDV)-induced
lymphoma progression
- A biodynamical model of human T-cell proliferative
disorders
- Current methodologies for characterization of tumor directed
immune response
"
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