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Signal Transduction (Hardcover, 3rd edition)
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Signal Transduction (Hardcover, 3rd edition)
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A reference on cellular signaling processes, the third edition of
Signal Transduction continues in the tradition of previous
editions, in providing a historical overview of how the concept of
stimulus-response coupling arose in the early twentieth century and
shaped our current understanding of the action of hormones,
cytokines, neurotransmitters, growth factors and adhesion
molecules. In a new chapter, an introduction to signal
transduction, the book provides a concise overview of receptor
mechanisms, from receptor - ligand interactions to
post-translational modifications operational in the process of
bringing about cellular changes. The phosphorylation process, from
bacteria to men, is discussed in detail. Signal transduction third
edition further elaborates on diverse signaling cascades within
particular contexts such as muscle contraction, innate and adaptive
immunity, glucose metabolism, regulation of appetite, oncogenic
transformation and cell fate decision during development or in stem
cell niches. The subjects have been enriched with descriptions of
the relevant anatomical, histological, physiological or
pathological condition.
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