The Covid-19 pandemic changed the world. Indeed a real race took
place worldwide between SARS-CoV-2 on the one hand and researchers
on the other – especially those specializing in messenger RNA
vaccines. Four years after its emergence, the pandemic is not over,
but some decisive battles have been won, thanks to the great
success of mRNA vaccines. The Marathon of The Messenger presents
the history of these mRNA vaccines, combining a scientific
background with historical and economic perspectives. It appears
that an important page in the history of these new vaccines was
written in Europe, thanks to the crucial work of German and French
scientists; this effort began in 1993 and continues to this day. In
the face of a prevailing single-mindedness, these researchers
pushed through a new therapeutic concept and defined the
biotechnological keys that would open the way to the production of
therapeutic messenger RNA in the fight against cancer and viral
infections. Written for a broad audience and accompanied by
humorous cartoons, this book will appeal to anyone looking for
scientific and historical answers about mRNA vaccines. Readers will
discover not only the technical and scientific knowledge of how
these vaccines work, but also the economic levers that were
necessary to create this technology. This book has been written in
collaboration with Dr. Steve Pascolo, former director of CureVac,
and the RNA messenger expert Professor Chantal Pichon. It also
features a preface by Dr. Pierre Meulien, former director of the
European Union public-private partnership Innovative Medicines
Initiative (IMI).
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