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Optimal Cancer Screening (Paperback)
Loot Price: R1,209
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Optimal Cancer Screening (Paperback)
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A dynamic stochastic model for colon and rectum cancer is developed
to obtain the optimal ages to perform colonoscopies. The currently
recommended guideline for colonoscopy is to test at ages 50, 60,
70, 80 and 90. Our Monte Carlo simulation yields a cost/life-year
saved of $54,919.62 for the official policy. We ask the following:
if we could reallocate the 5 tests between the ages of 50 and 90,
which ages for testing would give the lowest cost/life-year saved?
Of the 91,309 possible policies 43,026, or 47%, have a better cost
per life-year saved than the currently recommended guidelines. The
policy with the lowest cost is to test at the ages of 64, 71, 73,
79, 85 with a cost of $38,081.37 per life-year saved. An
improvement of 30% in the cost/life-year saved. The framework
developed in this paper can be further used to evaluate the cost
effectiveness of current guidelines for other cancers. The policies
can be personalized by sex and race to have better cost-
effectiveness ratios. Finally, guidelines can be developed to
equate cost per life-year saved across different cancers.
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