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Gene Genealogies, Variation and Evolution: A primer in coalescent theory (Paperback, New)
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Gene Genealogies, Variation and Evolution: A primer in coalescent theory (Paperback, New)
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Coalescent theory tells us what gene genealogies are expected to
look like if populations have different demographic histories -
i.e, population size, structure, etc. The aim of this book is to
provide an accessible introduction to Coalescent Theory with a view
towards data analysis. Coalescent Theory has in the last two
decades moved from being an obscure technique that appealed to
mathematical population geneticists to a central tool in data
analysis of DNA sequences. The completion of the sequencing of the
human genome and accompanying determination of SNPs and haplotypes
will increase its importance even further. This textbook, rich in
examples and illustrations, is suitable for a graduate course in
statistics, population-, molecular-, and medical genetics.
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