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Books > Medicine > Clinical & internal medicine > Rheumatology
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New Developments in Antirheumatic Therapy (Paperback, Softcover reprint of the original 1st ed. 1989)
Loot Price: R1,482
Discovery Miles 14 820
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New Developments in Antirheumatic Therapy (Paperback, Softcover reprint of the original 1st ed. 1989)
Series: Inflammation and Drug Therapy Series, 3
Expected to ship within 10 - 15 working days
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Total price: R1,502
Discovery Miles: 15 020
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At present we may be at the cross-roads in the therapeutic
approaches we have for the treatment of the 100 or more rheumatic
conditions. This is be cause we now recognise that although some
advances have been made with the development of a large range of
non-steroidal and steroidal drugs during the past two decades or
so, we now recognise that many, if not all, of these have rather
limited effects on many of the disease processes which underlie the
manifestations of the various rheumatic states. Advances in
molecular bi- 010gy in the past 5-10 years have enabled these tools
to be applied extensive ly for developing further our understanding
of the rheumatic disease processes. In some cases these molecular
tools (e. g., ), -interferon, interleukin- 2, T-cell antibodies)
have been directly employed as therapies themselves. While the
outcome from trials with such agents in rheumatoid arthritis in
particular has not been as would have been hoped, these results as
with cy closporin A and low-dose methotrexate in the therapy of
rheumatoid arth ritis have given us important indications for the
approach employing what are generally described as
"immunomodulators" to control this disease. But this may not be the
same type of approach which is desirable for all types of rheumatic
conditions. Indeed, even the way which the present range of drugs
and other therapies are applied may not be the most effective and
safe means of treating different types of arthritic conditions."
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