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Isolated Liver Perfusion for Hepatic Tumors (Paperback, Softcover reprint of the original 1st ed. 1998)
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Discovery Miles 29 930
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Isolated Liver Perfusion for Hepatic Tumors (Paperback, Softcover reprint of the original 1st ed. 1998)
Series: Recent Results in Cancer Research, 147
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The contributions in this book were originally presented at the
workshop "Research and Clinical Application of Isolated Liver
Perfusion for Hepatic Tumors" held on 28 February to 1 March 1997
in Hanover, Germany. The workshop was planned to bring together
groups working with isolated liver perfusion techniques worldwide.
Experts from various countries were invited to pre sent and discuss
their experimental data and clinical results. USA par Groups from
Japan, The Netherlands, Sweden and the ticipated. At the beginning,
oncologists, surgeons and patholo gists presented possible
indications and the oncological back ground for therapeutic
isolated liver perfusion from their points of view. Based on data
from previous studies about loco regional chemotherapy and based on
the pathology of metastasis, it could be concluded that there is a
place for isolated liver perfusion in the therapy of liver cancer.
Second, different surgical techniques of isolated liver perfusion
were presented. These techniques var ied from a percutaneous
approach with extracorporeal chemofil tration to extended open
abdominal surgery. Perfusion of the liv er without a considerable
amount of drug reaching the systemic circulation proved to be
possible. The complex procedure with complicated extracorporeal
perfusion technique represented a disadvantage of the methods
presented. Further studies should simplify the technical and
surgical aspects. Intraoperative and postoperative management of .
patients undergoing isolated liver perfusion were also discussed.
Coagulopathy was one important aspect which can occur during
isolated liver perfusion. The per centage of leakage determined
systemic side effects."
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