Understand the latest experimental tools in structural biology with
this pioneering work Structural biology seeks to understand the
chemical mechanisms and functions of biological molecules, such as
proteins, based on their atomic structures. Until recently, these
structures have been studied only statically, using procedures
which deliberately freeze atomic motion. However, freezing
eliminates the rapid structural motions so essential to biological
activity and function; the molecules are inactive. But with the
recent development of X-ray free electron laser (XFEL) sources,
efforts to conduct dynamic experiments have expanded using the
principles of dynamics and kinetics to capture active biological
molecules as they function. Dynamics and Kinetics in Structural
Biology promotes the development of these experiments and their
successful application. It grounds readers in the foundational
principles of dynamics and kinetics; proceeds through extended
discussions of experimental procedures, data analysis techniques;
and explores experimental frontiers in structural dynamics. The
book will aid researchers to gather and interpret cutting-edge data
on the dynamic structure of biological molecules, under conditions
where they retain their biological functions. Dynamics and Kinetics
in Structural Biology offers readers: Authorship by founding
figures in the field In-depth presentation of time-resolved X-ray
crystallography, solution scattering, and more A pioneering
contribution to a rapidly developing field of study Dynamics and
Kinetics in Structural Biology is essential reading for graduate
students, scientists, researchers and industry professionals
engaged in structural studies of biological systems. Industry
professionals considering dynamic studies in the development of new
product lines will also benefit.
General
| Imprint: |
John Wiley & Sons
|
| Country of origin: |
United States |
| Release date: |
December 2023 |
| First published: |
2022 |
| Authors: |
Keith Moffat
• Eaton E. Lattman
|
| Dimensions: |
244 x 170mm (L x W) |
| Format: |
Hardcover - Sewn / Cloth over boards
|
| Pages: |
304 |
| ISBN-13: |
978-1-119-69628-5 |
| Categories: |
Books
Promotions
|
| LSN: |
1-119-69628-3 |
| Barcode: |
9781119696285 |
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