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Risedronate Effects on Bone Metastasis of Rat Mammary Tumor Cell Lines (Paperback) Loot Price: R1,106
Discovery Miles 11 060
Repayment Terms: R104 pm x 12*
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Risedronate Effects on Bone Metastasis of Rat Mammary Tumor Cell Lines (Paperback): Kelli Boyd, Gregory Hall, Elizabeth Howerth

Risedronate Effects on Bone Metastasis of Rat Mammary Tumor Cell Lines (Paperback)

Kelli Boyd, Gregory Hall, Elizabeth Howerth

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List price R1,396 Loot Price R1,106 Discovery Miles 11 060 | Repayment Terms: R104 pm x 12* You Save R290 (21%)

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When compared to MTA cells, MTB-01 cells were susceptible to risedronateinduced apoptosis, had decreased ability to bind to risedronate-treated bone, and did not produce MMP-2 or MMP-9 proteases. MTA cells were less susceptible to risedronateinduced apoptosis and produced MMP-2. Additionally, adhesion of MTA cells to bone matrix was not diminished by risedronate treatment. Our results suggest that the nonresponsive nature of the MTA cell line may be due to MMP-2 production (possibly allowing ongoing destruction of risedronate-treated bone), continued adhesion to risedronate-treated bone matrix, and decreased susceptibility to risedronate-induced apoptosis.

General

Imprint: Lap Lambert Academic Publishing
Country of origin: Germany
Release date: February 2012
First published: February 2012
Authors: Kelli Boyd • Gregory Hall • Elizabeth Howerth
Dimensions: 229 x 152 x 8mm (L x W x T)
Format: Paperback - Trade
Pages: 128
ISBN-13: 978-3-8473-4152-9
Categories: Books > Professional & Technical > Veterinary science > General
LSN: 3-8473-4152-9
Barcode: 9783847341529

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