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Methods in Biological Oxidative Stress (Hardcover, 2003 ed.)
Loot Price: R2,883
Discovery Miles 28 830
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Methods in Biological Oxidative Stress (Hardcover, 2003 ed.)
Series: Methods in Pharmacology and Toxicology
Expected to ship within 10 - 15 working days
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Oxidative damage appears to play a central role in the development
of a wide range of tissue pathology, including neurodegenerative
disease, drug side-effects, xenobiotic toxicity, carcinogenesis,
and the aging process, to name just a few. Because of the
centrality of oxidative processes to normal and abnormal tissue
function, it has become imperative to develop appropriate
analytical techniques to facilitate the quantitation of significant
reactants. Without advances in methodology, corresponding advances
in our knowledge of underlying biochemical events will be
necessarily limited. Drs. Hensley and Floyd have done an
outstanding job of assembling the work of world-class experts into
Methods in Biological Oxidative Stress. The contributors have
presented concise, yet thorough, descriptions of the
state-of-the-art methods that any investigator working in the field
needs to access. Mannfred A. Hollinger v Preface Free radicals and
reactive oxidizing agents were once ignored as biochemical entities
not worth close scrutiny, but are now recognized as causes or
contributing factors in dozens, if not hundreds, of disease states.
In addition, free radical metabolisms of xenobiotics have become
increasingly important to pharmacologists. Accordingly, the need
has arisen to accurately quantify reactive oxygen species and their
byproducts. Methods in Biological Oxidative Stress is practical in
scope, providing the details of up-to-date techniques for measuring
oxidative stress and detecting oxidizing agents both in vitro and
in vivo. The contributors are recognized experts in the field of
oxidative stress who have developed novel strategies for studying
biological oxidations.
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