Recent years have witnessed a resurgence of interest in the
possible role of brain acetylcholine in neuropsychiatric disease.
Research in this area has involved the renewed investigation of the
cholinomimetics physostigmine and arecoline, and has been
facilitated by the development of new potential cholinomimetics
such as dimethylaminoethanol (Deanol) and choline chloride. Current
investigators also have taken advantage of new approaches to
neurochemical studies. Increasingly sensitive assay techniques such
as gas chromatography/mass spectrometry have allowed investigators
to measure low concentra tions of choline and acetylcholine in
brain tissues. Improved neuroanatomical procedures such as
immunohistochemical staining and the use of microelectrodes and
micropipets have enabled skilled investigators to begin to map
central acetylcholine pathways and to dissect the component parts
of the complex interactions between brain acetylcholine and other
neurotransmitters. The convergence of data from both clinical and
basic studies now suggest that brain acetylcholine may be involved
in affective illness, several movement disorders, and some
cognitive disturbances. The purpose of this book is to summarize
recent clinical and pre-clinical investigations on the possible
role of brain acetylcholine in several neurological and psychiatric
disorders. The volume is divided into six major sections: (1) Brain
Acetylcholine and Psychiatric Disorders; (2) Brain Acetylcholine
and Movement Disorders; (3) Brain Acetylcholine and Cognitive
Function; (4) The Electrophysiology of Cholinergic Agents; (5)
Interactions of Brain Acetylcholine and Other Neurotransmitters;
(6) Biochemical and Pharmacological Aspects of CholinergiC
Treatment Strategies."
General
| Imprint: |
Springer-Verlag New York
|
| Country of origin: |
United States |
| Release date: |
November 2012 |
| First published: |
1979 |
| Editors: |
Kenneth L. Davis
|
| Dimensions: |
244 x 170 x 38mm (L x W x T) |
| Format: |
Paperback
|
| Pages: |
598 |
| Edition: |
1979 ed. |
| ISBN-13: |
978-1-4613-2936-7 |
| Categories: |
Books >
Medicine >
Other branches of medicine >
Psychiatry
|
| LSN: |
1-4613-2936-1 |
| Barcode: |
9781461329367 |
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