This compendium of research material on the role of oxidative
stress in animal disease and morbidity examines both the general
and the specific. Sourced from scientists, veterinarians, and
members of the medical community from around the world, it includes
chapters on our wider understanding of the corrosive function of
free radicals in cell biology as well as focusing on the interplay
between oxidative stress and metabolism in a variety of animal
species including dogs, ruminants and birds. Since biogerontologist
Denham Harman first posited that free radicals arising from the
metabolic activity of oxygen play a central role in aging and
disease, a mass of evidence has accumulated linking oxidative
stress and biological degradation. We now understand that living in
an aerobic environment inevitably leads to the production of free
radicals that go on to attack biological membranes and lipoproteins
via oxidation in a process called lipid peroxidation. Reacting with
carbon-based molecules such as polyunsaturated fatty acids, these
free radicals cause oxidative stress and tissue damage. The purpose
of Studies on Veterinary Medicine is to inform clinicians, students
and others of the plethora of consequences that free radical damage
(ROS) has on various cells, tissues, and organs, as well as in
different species of animals. The chapters also analyze the effects
of oxidative stress on aging and various morbidities such as
diabetes, cognitive dysfunction and heart disease. Contributors
variously present their interpretation of the role played by
oxidative damage in disease and assess the benefits of antioxidant
therapies.
General
Imprint: |
HumanaPress
|
Country of origin: |
United States |
Series: |
Oxidative Stress in Applied Basic Research and Clinical Practice |
Release date: |
September 2014 |
First published: |
2011 |
Editors: |
Lester Mandelker
• Peter Vajdovich
|
Dimensions: |
235 x 155 x 14mm (L x W x T) |
Format: |
Paperback
|
Pages: |
260 |
Edition: |
2011 ed. |
ISBN-13: |
978-1-61779-728-6 |
Categories: |
Books >
Professional & Technical >
Veterinary science >
General
|
LSN: |
1-61779-728-6 |
Barcode: |
9781617797286 |
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