Volume 12 in this series explores the latest experimental and
clinical uses of stem cells in the treatment of disease and of
injuries and reviews methods for isolating multipotent
endothelial-like cells from human adipose tissue and discusses
clinical applications in cell therapy and regenerative
medicine.
The book is organized in five parts: Cancer Stem Cells,
Pluripotent Stem Cells, Dendritic Stem Cells, Regenerative Medicine
and General Applications. The first section includes chapters on
histamine in the neural and cancer stem cell niches and emerging
concepts of stem cell organization in the normal lung and in lung
cancer. The section on Pluripotent Stem Cells includes discussion
of the differentiation of dendritic cells from human induced
pluripotent stem cell and the molecular mechanisms involved in
reprogramming human somatic cells to generate induced pluripotent
stem cells. Additional chapters cover the differentiation of
induced pluripotent stem cells into functional cardiomyocytes,
characteristics of satellite cells and multipotent adult stem cells
in the skeletal muscle. The section on Dendritic Stem Cells
explores the critical role of notch signaling in the
differentiation and function of dendrite. Other chapters cover
hypertensive emergencies in children after stem cell
transplantation and overcoming the radio resistance of lung cancer
stem cells. The section on Regenerative Medicine reports on
experiments on improved renal revascularization in pigs using stem
cells and phenotypic correction of murine Hemophilia A using
cell-based therapy. The concluding section, General Applications,
discusses such topics as methods in mathematical modeling for stem
cells, as well as molecular and functional characterization of
human adipocytes.
Like its eleven predecessors in the series," " this volume
stands out for its comprehensive approach, its roster of some 51
expert contributors representing a dozen different countries and
its up-to-date review of leading-edge technology and methods.
General
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