This third edition is a comprehensive and extended study about the
best known approaches for preparing the main types of glycosides,
covering the classic and more recent glycosylation reactions used
for preparing simple and challenging glycosides currently used as
potent antiviral and antineoplastic drugs, or fluorogenic
substrates used for enzymatic detection in cell biology.
 Besides, this new edition provides more examples of the
glycosidic methodologies followed for preparing complex
glycoconjugates such as glycoproteins and glycosphingolipids and
gangliosides used as adjuvants or as synthetic vaccines candidates.
Also, additional mechanistic evidence is presented for better
understanding of the glycosylation reaction, trying to identify the
variables mainly depending on protecting and leaving groups, as
well as catalyst and reaction condition which altogether directs
the anomeric stereo control. A chapter on the glycoside hydrolysis
is included in view of the increasing interest in the use of
biomass as a natural and renewable source for obtaining important
intermediates or products used in food or valuable materials. The
author includes information in the characterization of glycosides
section with the aim of giving additional tools for the structural
assignment through NMR, X-Ray and mass spectra techniques.
General
Imprint: |
Springer Nature Switzerland AG
|
Country of origin: |
Switzerland |
Release date: |
April 2023 |
First published: |
2022 |
Authors: |
Marco Brito-arias
|
Dimensions: |
235 x 155mm (L x W) |
Pages: |
530 |
Edition: |
3rd ed. 2022 |
ISBN-13: |
978-3-03-097856-3 |
Categories: |
Books
|
LSN: |
3-03-097856-7 |
Barcode: |
9783030978563 |
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