An Up-to-Date Physical Science Toolbox for Probing Biology
Biophysics: Tools and Techniques for the Physics of Life covers the
experimental, theoretical and computational tools and techniques of
biophysics. It addresses the purpose, science, and application of
all physical science instrumentation, theoretical analysis and
biophysical computational methods used in current research labs.
The book first presents the historical background, concepts, and
motivation for using a physical science toolbox to understand
biology. It then familiarizes undergraduate students from the
physical sciences with essential biological knowledge. The text
subsequently focuses on experimental biophysical techniques that
primarily detect biological components or measure/control
biological forces. The author describes the science and application
of key tools used in imaging, detection, general quantitation, and
biomolecular interaction studies, which span multiple length and
time scales of biological processes both in the test tube and in
the living organism. Moving on to theoretical and computational
biophysics tools, the book presents analytical mathematical methods
and numerical simulation approaches for tackling challenging
biological questions including exam-style questions at the end of
each chapter as well as step-by-step solved exercises. It concludes
with a discussion of the future of this exciting field. Future
innovators will need to be trained in multidisciplinary science to
be successful in industry, academia, and government support
agencies. Addressing this challenge, this textbook educates future
leaders on the development and application of novel physical
science approaches to solve complex problems linked to biological
questions. Features: Provides the full, modern physical science
toolbox of experimental, theoretical and computational techniques,
such as bulk ensemble methods, single-molecule tools, live-cell and
test tube methods, pencil-on-paper theory approaches and
simulations Incorporates worked examples for the most popular
physical science tools, including full diagrams and a summary of
the science involved in the application of the tool Reinforces the
understanding of key concepts and biological questions A solutions
manual is available upon qualifying course adoption. Mark C. Leake
holds the Anniversary Chair of Biological Physics, and is
Coordinator of the Physics of Life Group at the University of York,
and Chair of the UK Physics of Life Network PoLNET. He heads an
interdisciplinary research team in the field of single-molecule
biophysics using cutting-edge biophotonics, state-of-the-art
genetics and advanced computational and theory tools. His work is
highly cited, and he has won many fellowships and prizes.
General
Imprint: |
Taylor & Francis
|
Country of origin: |
United Kingdom |
Release date: |
November 2023 |
First published: |
2024 |
Authors: |
Mark C. Leake
|
Dimensions: |
280 x 210mm (L x W) |
Pages: |
438 |
Edition: |
2nd edition |
ISBN-13: |
978-1-03-237321-8 |
Categories: |
Books
|
LSN: |
1-03-237321-0 |
Barcode: |
9781032373218 |
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