This book provides the first and only comprehensive description
and detailed summary of the genetics, structure, function,
mechanisms of action, evolution and engineering of homing
endonucleases and inteins. These two unique protein superfamilies,
which are tied together through their frequent fusion and
coevolution, have generated considerable excitement for their
fundamental, structural, and functional properties, their evolution
as parasitic elements, and their widespread applications as gene
targeting agents and as instruments for the generation of modified
proteins and novel protein combinations.
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