This important book provides up-to-date information on a series of
topical issues relating to the approach to minimal residual disease
in breast cancer patients. It first explains how the study of
minimal residual disease and circulating and disseminated tumor
cells (CTCs/DTCs) can assist in the understanding of breast cancer
metastasis. A series of chapters then discuss the various
technologies available for the detection and characterization of
CTCs and DTCs, pinpointing their merits and limitations. Detailed
consideration is given to the relevance of CTCs and DTCs, and their
detection, to clinical research and practice. The role of other
blood-based biomarkers is also addressed, and the closing chapters
debate the challenges facing drug and biomarker co-development and
the use of CTCs for companion diagnostic development. This book
will be of interest and assistance to all who are engaged in the
modern management of breast cancer.
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