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In silico epitope prediction for meningococcal vaccine development (Paperback)
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In silico epitope prediction for meningococcal vaccine development (Paperback)
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The majority of invasive meningococcal disease in developed
countries is caused by Neisseria meningitidis with a serogroup B
capsule. Despite, the availability of vaccines for other serogroups
since the 1960s, no broadly effective vaccine has been developed
for prevention of meningococcal serogroup B disease. However, with
the increasing availability of microbial genome sequence
information along with the recent advancements in the field of
bioinformatics, it is now possible to identify potential protein
targets of immune response that would certainly be useful in
reducing the time and cost involved in the traditional study of
immunology. With this in mind, this book comprehensively
illustrates the utility of existing computational resources for in
silico epitope prediction and immune system modeling with special
reference to N. meningitidis serogroup B vaccine development.
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