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Advancing Therapeutic Development for Pain and Opioid Use Disorders Through Public-Private Partnerships - Proceedings of a Workshop (Paperback)
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Advancing Therapeutic Development for Pain and Opioid Use Disorders Through Public-Private Partnerships - Proceedings of a Workshop (Paperback)
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Chronic pain is one of the most prevalent, costly, and disabling
health conditions in the United States. Estimates show that more
than 11 percent of the American population suffer from chronic
pain, yet the federal pain research investment has been minimal. In
parallel with a gradual increased recognition of the problems of
treating chronic pain, the opioid epidemic has emerged as a growing
public health emergency. The intersection of these two crises lies
in the fact that an unintended consequence of treating pain has
been an increasing number of opioid prescriptions and diversion of
drugs for illicit purposes. In May 2017, the National Institutes of
Health (NIH), and the National Institute on Drug Abuse announced a
public?private partnership to develop solutions to the opioid
crisis and cut in half the time it takes to develop non-addictive
analgesics. To advance the planning of NIH's anticipated
public?private partnerships, the National Academies' Forum on
Neuroscience and Nervous Systems Disorders hosted a public workshop
that brought together a diverse group of stakeholders from
academia, federal agencies, advocacy organizations and companies
developing therapeutics for pain and opioid use disorders.
Participants discussed potential strategies to accelerate
development of non-addictive pain medications and treatments for
opioid use disorders. This publication summarizes the presentations
and discussions from the workshop. Table of Contents Front Matter 1
Introduction and Background 2 Exploring Challenges to Developing
Treatments for Pain and Opioid Use Disorders 3 Exploring the State
of the Science and Preclinical Models for Pain Therapeutic
Development 4 Clinical Development of Non-Addictive Pain
Medications 5 Therapeutic Development for Opioid Use Disorders and
Overdose Prevention and Reversal 6 PublicPrivate Partnerships to
Advance Pain and Opioid Use Disorders Research and Development
Appendix A References Appendix B Workshop Agenda Appendix C
Registered Attendees
General
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