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The Emerging Field of Human Neural Organoids, Transplants, and Chimeras - Science, Ethics, and Governance (Paperback)
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The Emerging Field of Human Neural Organoids, Transplants, and Chimeras - Science, Ethics, and Governance (Paperback)
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Each year, tens of millions of individuals in the U.S. suffer from
neurological and psychiatric disorders including neurodegenerative
diseases such as Alzheimer's Disease and Parkinson's Disease, and
psychiatric disorders such as autism spectrum disorder, depression
and schizophrenia. Treatments for these diseases are often
completely lacking or only partially effective, due in large part
to the difficulty of conducting brain research and the complexity
of the brain itself. Researchers in recent years have developed new
models to better represent and study the human brain. The three
models considered in this report, all of which generate and use
pluripotent stem cells from healthy individuals and patients, are
human neural organoids, human neural transplants, and human-animal
neural chimeras. The Emerging Field of Human Neural Organoids,
Transplants, and Chimeras: Science, Ethics, and Governance reviews
the status of research, considers its benefits and risks, discusses
associated ethical issues, and considers governance mechanisms for
this type of research. Table of Contents Front Matter Summary 1
Introduction 2 The Science of Human Neural Organoids, Transplants,
and Chimeras 3 Ethical Concerns 4 Oversight and Governance 5 Public
Engagement 6 Findings of the Committee References Appendix A:
Biographies of Committee and Staff Members Appendix B: Committee
Meeting Agendas
General
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