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Enhancing Scientific Reproducibility in Biomedical Research Through Transparent Reporting - Proceedings of a Workshop (Paperback)
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Enhancing Scientific Reproducibility in Biomedical Research Through Transparent Reporting - Proceedings of a Workshop (Paperback)
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Sharing knowledge is what drives scientific progress - each new
advance or innovation in biomedical research builds on previous
observations. However, for experimental findings to be broadly
accepted as credible by the scientific community, they must be
verified by other researchers. An essential step is for researchers
to report their findings in a manner that is understandable to
others in the scientific community and provide sufficient
information for others to validate the original results and build
on them. In recent years, concern has been growing over a number of
studies that have failed to replicate previous results and evidence
from larger meta-analyses, which have pointed to the lack of
reproducibility in biomedical research. On September 25 and 26,
2019, the National Academies of Science, Engineering, and Medicine
hosted a public workshop in Washington, DC, to discuss the current
state of transparency in the reporting of preclinical biomedical
research and to explore opportunities for harmonizing reporting
guidelines across journals and funding agencies. Convened jointly
by the Forum on Drug Discovery, Development, and Translation; the
Forum on Neuroscience and Nervous System Disorders; the National
Cancer Policy Forum; and the Roundtable on Genomics and Precision
Health, the workshop primarily focused on transparent reporting in
preclinical research, but also considered lessons learned and best
practices from clinical research reporting. This publication
summarizes the presentation and discussion of the workshop. Table
of Contents Front Matter 1 Introduction 2 Transparency and Trust 3
Approaches to Cultivate Transparent Reporting in Biomedical
Research 4 Lessons Learned and Best Practices 5 Checklists and
Guidelines 6 Toward Minimal Reporting Standards for Preclinical
Biomedical Research 7 Stakeholder Opportunities for Promoting
Transparent Reporting Appendix A: References Appendix B: Background
Discussion Document: Selected Guidelines for Transparent Reporting
Appendix C: Workshop Agenda
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