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Nonhuman Primate Models in Biomedical Research - State of the Science and Future Needs
Loot Price: R1,240
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Nonhuman Primate Models in Biomedical Research - State of the Science and Future Needs
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Nonhuman primates represent a small fraction of animals used in
biomedical research, but they remain important research models due
to their similarities to humans with respect to genetic makeup,
anatomy, physiology, and behavior. Limitations in the availability
of nonhuman primates have been exacerbated by the COVID-19 pandemic
and recent restrictions on their exportation and transportation,
impacting National Institutes of Health (NIH)-funded research
necessary for both public health and national security.
Additionally, there is continued interest in understanding whether
and how nonanimal models can be used to answer scientific questions
for which nonhuman primates are currently used. At the direction of
the U.S. Congress, NIH asked the National Academies of Sciences,
Engineering, and Medicine to convene an expert committee to conduct
a landscape analysis of current and future use of nonhuman primates
in NIH-supported biomedical research, as well as opportunities for
new approach methodologies to complement or reduce reliance on
nonhuman primate models. This report provides the committee
findings and conclusions. Table of Contents Front Matter Summary 1
Introduction 2 Contribution of Nonhuman Primate Models to Advances
in Human Health 3 Current Landscape of Use and Availability of
Nonhuman Primates for NIH-Supported Biomedical Research 4 The
Landscape of New Approach Methodologies 5 Future Needs and
Opportunities for Nonhuman Primate Models in Biomedical Research
Appendix A: Study Approach and Methods Appendix B: Data on Nonhuman
Primate Use in NIH-Supported Biomedical Research Appendix C:
Biographical Sketches of Committee Members and Staff Appendix D:
Disclosure of Unavoidable Conflicts of Interest
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