Bioinformatics of Genome Regulation and Structure II (Hardcover, 2006 ed.)

The last 15 years in development of biology were marked with accumulation of unprecedentedly huge arrays of experimental data. The information was amassed with exclusively high rates due to the advent of highly efficient experimental technologies that provided for high throughput genomic sequencing; of functional genomics technologies allowing investigation of expression dynamics of large groups of genes using expression DNA chips; of proteomics methods giving the possibility to analyze protein compositions of cells, tissues, and organs, assess the dynamics of the cell proteome, and reconstruct the networks of protein-protein interactions; and of metabolomics, in particular, high resolution mass spectrometry study of cell metabolites, and distribution of metabolic fluxes in the cells with a concurrent investigation of the dynamics of thousands metabolites in an individual cell. Analysis, comprehension, and use of the tremendous volumes of experimental data reflecting the intricate processes underlying the functioning of molecular genetic systems are unfeasible in principle without the systems approach and involvement of the state-of-the-art information and computer technologies and efficient mathematical methods for data analysis and simulation of biological systems and processes. The need in solving these problems initiated the birth of a new science- postgenomic bioinformatics or systems biology in silico.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Release date:	November 2005
First published:	2006
Editors:	Nikolay Kolchanov • Ralf Hofestaedt • Luciano Milanesi
Dimensions:	234 x 156 x 31mm (L x W x T)
Format:	Hardcover
Pages:	560
Edition:	2006 ed.
ISBN-13:	978-0-387-29450-6
Categories:	Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > General Promotions
LSN:	0-387-29450-3
Barcode:	9780387294506

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