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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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Annotating New Genes - From in Silico Screening to Experimental Validation (Hardcover, Annotated edition)
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Annotating New Genes - From in Silico Screening to Experimental Validation (Hardcover, Annotated edition)
Series: Woodhead Publishing Series in Biomedicine
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In recent years, a number of academic and commercial software
packages and databases have been developed for the analysis and
screening of biological data; however, the usability of these data
is compromised by so-called novel genes to which no biological
function is assigned. Annotating new genes outlines an approach to
the analysis of evolutionary-conserved, heart-enriched genes with
unknown functions, offering a step-by-step description of the
procedure from screening to validation. The book begins by offering
an introduction to the databases and software available, before
moving on to cover programming guidelines, including a specific
case study on the use of C-It for in silico screening. The second
half of the book offers a step-by-step guide to experimental
validation concepts and procedures, as well as an overview of
additional potential applications of this approach in the field of
stem cells and tissue regeneration, before a concluding chapter
summarises the concepts and theories presented.
Focuses not only on screening but also on biological
validationsProvides details of databases and software (web
interface) products for biologists with minimal computation
skillsOffers a step-by-step outline of the procedure involved
General
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