Chromatin Readers in Health and Disease, Volume 35, a new release
in the Translational Epigenetics series, gathers and makes
actionable our current understanding of how chromatin readers
regulate access to genetic information, and how their aberrant
regulation can contribute to human pathologies. Chromatin readers
discussed include 14-3-3 Dinshaw, ADD, Ankyrin, BAH, BET, BIR,
BRCT, bromodomains and Kac readers, chromodomains and chromobarrel
readers, citrullination readers, macrodomains and poly-ADP-ribose
readers, MBT, PHD and double PHD, PWWP, SUMO (H4K12) readers, Tudor
and TTD, UDR and ubiquitin, WD40, YEATS (crotonyl reader), MBD,
SRA, and Methyl-RNA readers. In the book, more than a dozen leaders
in the field examine a range of protein readers, their relationship
to human disease, and the early therapeutics that act as chromatin
signaling factors to treat cancers and Huntington's disease, among
other disorders.
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