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Epstein-Barr Virus and Human Disease (Hardcover, 1987 ed.)
Loot Price: R5,529
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Epstein-Barr Virus and Human Disease (Hardcover, 1987 ed.)
Series: Experimental Biology and Medicine, 15
Expected to ship within 10 - 15 working days
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Since its discovery as the cause of infectious mononucleosis in
1964, the Epstein-Barr virus (EBV) has been etiologically
implicated in an increasing number of human diseases. Generally
considered the first human oncogenic virus because of a number of
studies linking it with Burkitt's lymphoma and nasopharyngeal
carcinoma (NPC), as well as its documented oncogenicity in nonhuman
primates, EBVhas served as a model for identifying subsequent
candidate oncogenic viruses and the stimulus for Evans' revision of
the Henle-Koch postulates to accommodate the problems in proving
viral oncogenicity in humans. Research on the role of EBV in human
cancer was particularly en hanced (a) by the pioneering work of
Werner and Gertrude Henle, and (b) by the coordinated efforts of
the Special Virus Leukemia Program and its successors, the Special
Virus Cancer Program and the Virus Cancer Program of the National
Cancer Institute (NCI). Initiated by Dr. Frank J. Rauscher, who
subsequently became director of the Ncr and is now Vice-President
of the American Cancer Society, and expanded by Dr. John B.
Moloney, whose contributions to cancer research were honored at
this Second International Symposium on EBV and Associated Malignant
Diseases, these NCI contract-sup ported programs brought together
investigators from all over the world to participate in a joint
effort to unravel the mystery of EBV behavior and pathogenicity. It
was these programs that gave us the opportunity to work with such
outstanding people as Professor Yohei Ito, to whom this book is
dedicated."
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