Schizophrenia is one of the most complex and disabling diseases to
affect mankind. Relatively little is known about its nature and its
origins, and available treatments are inadequate for most patients.
As a result, there are inevitable controversies about what causes
it, how to diagnose it, and how best to treat it. However, in the
past decade, there has been an explosion of new research, with
dramatic discoveries involving genetic etiology and epidemiological
risk factors. There has also been a catalog of new drugs coming to
market, and controversy about the relative advantages and
disadvantages of newer compared with older therapies. In addition,
developing technologies in genomics, molecular biology and
neuroimaging provide streams of new information.
This book represents a definitive, essential, and up-to-date
reference text on schizophrenia. It extensively and critically
digests and clarifies recent advances and places them within a
clinical context. The Editors (one American and one British),
highly respected clinical psychiatrists and researchers and
acknowledged experts on schizophrenia, have again assembled an
outstanding group of contributors from the USA, UK, Europe and
Australia, It will be of value to practising psychiatrists and to
trainees, as well as to clinical and neuroscience researchers
interested in keeping up with this field or coming into it.
The book consists of four sections: descriptive aspects,
biological aspects, physical treatments, and psychological and
social aspects. It reviews the theoretical controversies over
symptomatology, classification and aetiology (particularly
pertinent as DSM-V is being developed), the relationship of
schizophrenia to the other psychoses, the significance of positive
and negative symptoms and pre-morbid personality. It describes a
variety of approaches to integrating the vast research data about
schizophrenia, including neurodevelopmental, genetic,
pharmacological, brain imaging and psychological findings. The
biological treatment section reviews the comparative efficacy of
various drugs, the management of drug-resistant patients and both
neurological and metabolic complications. The final section looks
at psychological therapies, social outcomes, and the economics of
schizophrenia.
Highly Commended in the Psychiatry section of the 2012 BMA Book
Awards.
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