Genetic Analysis - Integrating Genes and Genomes (Hardcover)

The new advances in the field of genetics have led to numerous medical breakthroughs in the past few years. Genetic Analysis: Integrating Genes and Genomes provides an insight on the advances made in human genetics in the last few years. The editor has comprehensively assembled recent developments on the use of modern genetic analytical techniques and tools for answering biological questions related to genomic screening, mutations, gene and environment interactions, comparative and molecular genomic approaches for detecting genetic components of diseases. A better understanding of the genetic basis of disease can be achieved by studying genetic diversity across human populations. The interaction of gene and environment and their effects on human-specific developmental traits, genetic influences on methylation across the human life course, interplay of genes and lifestyle, genetic basis of disease in the context of migration, exposure to toxic metals like Lead, and calculation of genetic risk of diseases in unrelated individuals have been discussed. In addition, the synergistic effects of genes involved in cancer development, fructose-1,6-bisphosphatase deficiency, vitiligo, psoriasis, severe hypertriglyceridemia, and susceptibility to mycobacterial infection are explored in some chapters. Use of small interfering RNAs (siRNA), microRNAs and SINE sequences in screening systems have also been discussed to identify genes. In one of the articles, the general framework of whole exome sequence data analysis is outlined. Finally, we also present an article on ChemProt, a publicly available compilation of chemical-protein-disease annotation resources that enables the study of a molecule from cellular to clinical levels.

General

Imprint:	Delve Publishing
Country of origin:	Canada
Release date:	November 2016
Editors:	Prerna Pandey
Dimensions:	229 x 152mm (L x W)
Format:	Hardcover
Pages:	261
ISBN-13:	978-1-68095-741-9
Categories:	Books
LSN:	1-68095-741-4
Barcode:	9781680957419

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