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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins
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Ubiquitin Family Modifiers and the Proteasome - Reviews and Protocols (Hardcover, 2012)
Loot Price: R6,076
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Ubiquitin Family Modifiers and the Proteasome - Reviews and Protocols (Hardcover, 2012)
Series: Methods in Molecular Biology, 832
Expected to ship within 10 - 15 working days
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The ubiquitin-proteasome system (UPS) and ubiquitin-related
modifiers are not only involved in cellular protein quality control
but also in the regulation of many fundamental cellular
processes/pathways as well as in their disease-relevant
aberrations. Ubiquitin Family Modifiers and Proteasome: Reviews and
Protocols presents both novel developments in UPS research and
important methods related to the main recent advances in the field
of ubiquitin family modifiers. Divided into five convenient
sections, this volume focuses on the enzymology and substrate
identification of ubiquitin family modifiers, the recognition and
chain formation of these modifiers, the analysis of proteasome
biogenesis and function, protein quality control, and finally the
use of small molecules and strategies to study or manipulate the
function of the UPS and of ubiquitin family modifiers,
respectively. Written in the highly successful Methods in Molecular
Biology (TM) series format, chapters include introductions to their
respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible protocols, and notes on
troubleshooting and avoiding known pitfalls. Authoritative and
easily accessible, Ubiquitin Family Modifiers and Proteasome:
Reviews and Protocols will be of great use to investigators and
students engaged in both basic and applied research in life
sciences.
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