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Respiratory Infections and Tumours (Paperback, 1981 ed.)
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Respiratory Infections and Tumours (Paperback, 1981 ed.)
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There is a wide variation in the clinical syndromes and in the
severity of respiratory tract infections. This diversity is only
partly accounted for by the large number of infecting agents,
because a particular microorganism can itself result in different
illnesses. The age, fitness and state of immunity of the patient is
of great relevance, and the clinical features of a particular
infection vary accordingly. In terms of incidence of infection the
acute virus infections are far in the lead. Respiratory infections
can be broadly classified into acute and chronic. The acute
infections are generally due to bacteria, viruses, rickettsiae and
mycoplasma. Chronic infection is either bacterial, mycobacterial,
fungal or parasitic in origin. Protection Against Infection There
are three methods by which man can protect himself against
infections of the respiratory tract-mechanical barriers, phago
cytic cells and the immune response. Mechanical Barriers The cough
reflex protects the lung against inhaled irritant sub stances and
larger particles. Smaller particles will be trapped by the layer of
mucus which covers the respiratory tract. The ciliated epithelium
maintains a constant upward flow of the mucus and via this
mucociliary escalator expels particles from the respiratory tract.
2 Infections Infection can occur when these mechanical barriers are
altered, and the defect in the mucociliary lining accounts for the
increased susceptibility to infection in chronic bronchitis and
bronchiectasis.
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