This book identifies and analyzes the genetic basis of bone
disorders in humans and demonstrates the utility of mouse models in
furthering the knowledge of mechanisms and evaluations of
treatments. The book is aimed at all students of bone biology and
genetics, and with this in mind, it includes general introductory
chapters on genetics and bone biology and more specific
disease-orientated chapters, which comprehensively summarize the
clinical, genetic, molecular genetic, animal model, functional and
molecular pathology, diagnostic, counselling and treatment aspects
of each disorder.
Saves academic, medical, and pharma researchers time in quickly
accessing the very latest details on a broad range of genetic bone
issues, as opposed to searching through thousands of journal
articles.
Provides a common language for bone biologists and geneticists
to discuss the development of bone cells and genetics and their
interactions in the development of disease Researchers in all areas
bone biology and genetics will gain insight into how clinical
observations and practices can feed back into the research cycle
and will, therefore, be able to develop more targeted genomic and
proteomic assays
For those clinical researchers who are also MDs, correct
diagnosis (and therefore correct treatment) of bone diseases
depends on a strong understanding of the molecular basis for the
disease.
General
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