Oral squamous cell carcinoma is the sixth most common malignancy
and is a major cause of cancer morbidity and mortality worldwide.
Recent discoveries have dramatically increased our understanding of
the most basic mechanisms controlling normal cell growth, and have
also greatly enhanced our ability to investigate the nature of the
biological processes that lead to cancer. Mathematical models
predict that 8-10 individual genetic aberrations are required for
progression to head and neck cancer alongwith hundreds of genetic
aberrations, the vast majority unrelated to their pathogenesis. The
challenge for modern genetic analysis is to differentiate
consequential genetic aberrations from the background events.
However, this explosion of information on cancer-specific
chromosomal aberrations can be utilized by the scientific community
only if compiled in easily accessible databases
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