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Genotoxicity Of Aliskiren In The Bone Marrow And Germ Cells Of Mice (Paperback)
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Genotoxicity Of Aliskiren In The Bone Marrow And Germ Cells Of Mice (Paperback)
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As there is a need to combat human diseases, many drugs are being
used in the medical field. Though these drugs control the disease,
when used in higher doses they may be toxic to the genetic system
of human beings. Antihypertensive drugs are the most widely
prescribed medications in the world. The duration of the
pharmacological treatment of hypertension may last for decades and,
therefore, patients are exposed to prolonged contact with these
drugs. Long-term treatments require documentation of long-term
safety and efficacy, including sensitive indices of genotoxic
damage. Important part of prescription for hypertensive patients is
Aliskiren, the third-generation renin inhibitor, prescribe for
patient of hypertension. However the present topic is to understand
the possible genotoxic effects of its long term use. This
scientific information makes the people aware to utilize drug in
preventive dose regimen and may be of interest to many
pharmaceutical companies, bulk pharmaceuticals and drug
authorities. The financial assistance received from the Gujarat
Council on Science and Technology (GUJCOST), Gandhinagar, Gujarat,
India to carry out this particular study is duly acknowledged.
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