Offering unique, comprehensive coverage of both basic science and
clinical scenarios, Clinical Immunology: Principles and Practice,
6th Edition, brings you up to date with every aspect of this
fast-changing field. It examines the molecular, cellular, and
immunologic bases of immunologic diseases and their broader
systemic implications; it also includes complete coverage of common
and uncommon immunologic disorders. Updated with all the latest
immunologic research and clinical implications, including
breakthrough immunotherapies and molecular-based treatment
protocols, this fully revised edition provides authoritative
guidance from some of the most respected global leaders in
immunology in one complete, well-illustrated volume. Includes
extensive revisions that reflect rapidly expanding research and
clinical advances, including breakthrough drug and immunotherapies
such as immune checkpoint inhibitors, immunotherapies for cancer,
precision medicine, and transfusion medicine. Contains new chapters
on COVID-19, immune responses, and the role of the immune system;
immunoregulatory deficiencies; immune checkpoints; CAR T cells,
including new cellular-based immunotherapy; gene therapy, including
CRISPR and gene selection; and a clinically focused chapter on
asthma. Provides new genetics content focused on data applications.
Addresses notable advances in key areas such as the importance of
the microbiota to normal immune system development and to the
pathogenesis of immunologic and inflammatory diseases;
relationships between the innate and adaptive immune systems;
progress in rapid and cost-effective genomics; cell signaling
pathways and the structure of cell-surface molecules; and many
more. Covers hot topics such as the role of genetics and genomics
in immune response and immunologic disease, atherosclerosis,
recurrent fever syndromes, aging and deficiencies of innate
immunity, the role of microbiota in normal immune system
development and in the pathogenesis of immunologic and inflammatory
diseases, and novel therapeutics. Features a user-friendly format
with color-coded boxes highlighting critical information on Key
Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic
Principles. Summarizes promising research and development
anticipated over the next 5-10 years with "On the Horizon" boxes
and discussions of translational research. An eBook version is
included with purchase. The eBook allows you to access all of the
text, figures and references, with the ability to search, customize
your content, make notes and highlights, and have content read
aloud.
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